The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 16, 2012

Filed:

May. 10, 2010
Applicants:

William Scott Caldwell, Winston-Salem, NC (US);

Gary Maurice Dull, Lewisville, NC (US);

Balwinder Singh Bhatti, Winston-Salem, NC (US);

Srishakumar Basawannappa Hadimani, Oak Creek, WI (US);

Haeil Park, Kangwon-do, KR;

Jared Miller Wagner, Stillwater, OK (US);

Peter A. Crooks, Nicholasville, KY (US);

Inventors:

William Scott Caldwell, Winston-Salem, NC (US);

Gary Maurice Dull, Lewisville, NC (US);

Balwinder Singh Bhatti, Winston-Salem, NC (US);

Srishakumar Basawannappa Hadimani, Oak Creek, WI (US);

Haeil Park, Kangwon-do, KR;

Jared Miller Wagner, Stillwater, OK (US);

Peter A. Crooks, Nicholasville, KY (US);

Assignee:

Targacept, Inc., Winston-Salem, NC (US);

Attorney:
Int. Cl.
CPC ...
A61K 31/44 (2006.01); A61P 25/00 (2006.01); C07D 213/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds incorporating aryl substituted olefinic amine are provided. Representative compounds are (4E)-N-methyl-5-(3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-pyrimidinyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-methoxy-3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(6-amino-5-methyl-3-pyridyl)-4-penten-2-amine, (2R)-(4E)-N-methyl-5-(3-pyridyl)-4-penten-2-amine, (2R)-(4E)-N-methyl-5-(5-isopropoxy-3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-bromo-3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-ethoxy-3-pyridyl)-4-penten-2-amine, (2S)-(4E)-N-methyl-5-(3-pyridyl)-4-penten-2-amine, (4E)-N-methyl-5-(5-isopropoxy-3-pyridyl)-4-penten-2-amine and (2S)-(4E)-N-methyl-5-(5-isopropoxy-3-pyridyl)-4-penten-2-amine.


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