The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8288389 B1

PDF
Full Text
Expired
Date of Patent:
Oct. 16, 2012

Filed:

Sep. 04, 2008
Applicants:

Desmond John Best, Essex, GB;

Sing Yeung Mak, Singapore, SG;

Barry Sidney Orlek, Essex, GB;

Geracimos Rassias, Stevenage, GB;

Pamela Joan Theobald, Essex, GB;

Inventors:

Desmond John Best, Essex, GB;

Sing Yeung Mak, Singapore, SG;

Barry Sidney Orlek, Essex, GB;

Geracimos Rassias, Stevenage, GB;

Pamela Joan Theobald, Essex, GB;

Assignee:

Glaxo Group Limited, Greenford, Middlesex, GB;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); C07D 309/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to 1-(1-methylethyl)-4-{[4-(tetrahydro-2H-pyran-4-yloxy)phenyl]carbonyl}piperazine or a pharmaceutically acceptable salt thereof, in particular the hydrochloride salt thereof and crystalline forms of the hydrochloride salt; to processes for the preparation of the compound or its salt; to compositions containing it; and to its use in the treatment or prophylaxis of neurological or psychiatric diseases, such as cognitive impairment, fatigue or a sleep disorder, for example in a mammal such as a human. The compound or a salt thereof has affinity for and is an antagonist and/or inverse agonist of the histamine H3 receptor.


Find Patent Forward Citations

Best, Desmond. (2012). Piperazine derivative having affinity for the histamine h3 receptor (U.S. Patent No. 8288389). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8288389

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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