The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 16, 2012
Filed:
Mar. 24, 2008
Jae-hong Kim, Goyang-si, KR;
Jung-a Choi, Seoul, KR;
Eun-young Kim, Seoul, KR;
Geun-young Kim, Chungju-si, KR;
Chul-min Kim, Masan-si, KR;
Ji-min Seo, Seoul, KR;
Hyun-ju Kim, Incheon, KR;
Jin-wook Lee, Daejeon, KR;
Jae-Hong Kim, Goyang-si, KR;
Jung-A Choi, Seoul, KR;
Eun-Young Kim, Seoul, KR;
Geun-Young Kim, Chungju-si, KR;
Chul-Min Kim, Masan-si, KR;
Ji-Min Seo, Seoul, KR;
Hyun-Ju Kim, Incheon, KR;
Jin-Wook Lee, Daejeon, KR;
Korea University Research & Business Foundation, Seoul, KR;
Abstract
The present invention relates to a new use of inhibitors of leukotriene B4 receptor BLT2 for treating human cancers. More particularly, the present invention relates to a pharmaceutical composition for treating human cancers comprising BLT2 inhibitors and a method for treating human cancers using BLT2 inhibitors. The present inventors revealed the role of BLT2 as a survival factor of human cancers, such as bladder, prostate, pancreatic, and breast cancer and found that the BLT2 inhibitors can be used as anti-cancer drugs. The present inventors revealed that BLT2 has an important role in metastasis of cancer cells and angiogenesis of tumor and demonstrated that the anti-cancer activity of the BLT2 inhibitors is accomplished by inducing the apoptosis of cancer cells, inhibiting the metastasis of cancer cells, or inhibiting the angiogenesis of tumor.