The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 16, 2012
Filed:
Mar. 30, 2009
Applicants:
Hiroshi Kido, Tokushima, JP;
Tsunetomo Takei, Tokushima, JP;
Dai Mizuno, Tokushima, JP;
Inventors:
Assignee:
The University of Tokushima, Tokushima, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 45/00 (2006.01); A61K 39/12 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention is an antigen-and-drug (AD) vehicle and a mucosal vaccine utilizing a novel synthetic peptide. The antigen-and-drug (AD) vehicle is capable of inducing the production of secretory IgA antibodies, and is a complex of a synthetic peptide having the following amino acid sequence: PVHLKRLm (e.g., peptide of SEQ ID NO 1, 6, or 7) or KnLm (e.g., peptide of SEQ ID NO 2, 3, or 8), and a lipid(s). The mucosal vaccine is obtainable by allowing a mucosal-immunity-IgA-inducing amount of an antigen to coexist with, contact, be captured by, or be adsorbed onto the AD vehicle.