The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 09, 2012

Filed:

Feb. 08, 2010
Applicants:

Samir M. Iqbal, Irving, TX (US);

Swati Goyal, Arlington, TX (US);

Shawn M. Christensen, Arlington, TX (US);

Mohammud R. Noor, Arlington, TX (US);

Inventors:

Samir M. Iqbal, Irving, TX (US);

Swati Goyal, Arlington, TX (US);

Shawn M. Christensen, Arlington, TX (US);

Mohammud R. Noor, Arlington, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01R 27/26 (2006.01); G01R 27/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

Devices, systems, and methods for detecting nucleic acid hybridization, including single nucleic base mutations at low concentrations, are disclosed, using surface-tethered hairpin loop oligonucleotide probes and metal-nanoparticles conjugated to a hybridization detection sequence that is capable of binding the stem region of the opened hairpin loop oligonucleotide probe, without the use of labeling or target modification and capable of recycling.


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