The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 09, 2012
Filed:
Nov. 26, 2009
Elena Ben Moha-lerman, Kiryat Ono, IL;
Tamar Nidam, Yehud, IL;
Meital Cohen, Petach-Tikva, IL;
Sharon Avhar-maydan, Givataym, IL;
Anna Balanov, Rehovot, IL;
Elena Ben Moha-Lerman, Kiryat Ono, IL;
Tamar Nidam, Yehud, IL;
Meital Cohen, Petach-Tikva, IL;
Sharon Avhar-Maydan, Givataym, IL;
Anna Balanov, Rehovot, IL;
Teva Pharmaceutical Industries Ltd., Petach-Tikva, IL;
Abstract
Gabapentin enacarbil was prepared and purified from intermediates such as 1-haloalkyl carbamate or carbonate and diacid acetal skeleton. For example, a 1-haloalkyl carbonate or carbamate was prepared by combining a Cto Calcohol or Cto Cprimary amine, a solvent selected from the group consisting of: acetonitrile, Cto Cketone, Cto Cether, Cto Cester, Cto Chydrocarbon and a combination thereof; a 1-haloalkyl haloformate of the following formula: wherein each X is independently selected from Br, I, or Cl; Ris alkyl or H; and a Cto Ctertiary amine.