The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 09, 2012
Filed:
Oct. 31, 2007
Applicants:
Zijian Xie, Saline, MI (US);
Joseph I. Shapiro, Toledo, OH (US);
Jiang Tian, Perrysburg, OH (US);
Inventors:
Assignee:
University of Toledo, Toledo, OH (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/08 (2006.01); C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
A method for regulating Src and its downstream signaling pathway which includes binding between Src and Na+/K+-ATPase is disclosed. The Na+/K+-ATPase/Src complex is a functional receptor for cardiotonic steroids such as ouabain. Also disclosed are Src inhibitors or activators which include either Na+/K+-ATPase or Src that interfere with the interaction between the Na/K-ATPase and Src, act via a different mechanism from ATP analogues, and is pathway (Na+/K+-ATPase) specific.