The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 09, 2012

Filed:

Apr. 02, 2009
Applicants:

Gerrit Schubert, Kelkheim, DE;

Joerg Rieke-zapp, Frankfurt, DE;

Johannes Keil, Frankfurt, DE;

Heinz-werner Kleemann, Bischofsheim, DE;

Reda Hanna, Allentown, PA (US);

Bao-guo Huang, Bridgewater, NJ (US);

Xiao-dong Wu, Bridgewater, NJ (US);

Yves Gouraud, Montfermeil, FR;

Inventors:

Gerrit Schubert, Kelkheim, DE;

Joerg Rieke-Zapp, Frankfurt, DE;

Johannes Keil, Frankfurt, DE;

Heinz-Werner Kleemann, Bischofsheim, DE;

Reda Hanna, Allentown, PA (US);

Bao-Guo Huang, Bridgewater, NJ (US);

Xiao-Dong Wu, Bridgewater, NJ (US);

Yves Gouraud, Montfermeil, FR;

Assignee:

Sanofi-Aventis Deutschland GmbH, Frankfurt am Main, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4035 (2006.01); C07D 209/46 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to processes for preparing (3-oxo-2,3-dihydro-1H-isoindol-1-yl)acetylguanidine derivatives of the formula I via 3-hydroxy-2,3-dihydro-1H-isoindol-1-one derivatives or 3-(2-carbamoylphenyl)-acrylic ester derivatives as intermediates, to a process for optical resolution, and to intermediates of the process according to the invention.


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