The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 09, 2012

Filed:

Jun. 19, 2009
Applicants:

John C. Mckew, Arlington, MA (US);

Katherine L. Lee, Newton, MA (US);

Lihren Chen, Bedford, MA (US);

Richard Vargas, Brighton, MA (US);

James D. Clark, Acton, MA (US);

Cara Williams, Methuen, MA (US);

Valerie Clerin, Watertown, MA (US);

Suzana Marusic, Reading, MA (US);

Kevin Pong, Robbinsville, NJ (US);

Inventors:

John C. McKew, Arlington, MA (US);

Katherine L. Lee, Newton, MA (US);

Lihren Chen, Bedford, MA (US);

Richard Vargas, Brighton, MA (US);

James D. Clark, Acton, MA (US);

Cara Williams, Methuen, MA (US);

Valerie Clerin, Watertown, MA (US);

Suzana Marusic, Reading, MA (US);

Kevin Pong, Robbinsville, NJ (US);

Assignee:

Pfizer Inc., New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/404 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention provides chemical inhibitors of the activity of various phospholipase enzymes, particularly cytosolic phospholipase Aenzymes (cPLA), more particularly including inhibitors of cytosolic phospholipase Aalpha enzymes (cPLAα). In some embodiments, the inhibitors have the Formula I: wherein the constituent variables are as defined herein.


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