The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 09, 2012

Filed:

May. 12, 2008
Applicants:

Makoto Inoue, Ibaraki, JP;

Mamoru Hasegawa, Ibaraki, JP;

Yoshikazu Yonemitsu, Chiba, JP;

Yui Harada, Saitama, JP;

Inventors:

Makoto Inoue, Ibaraki, JP;

Mamoru Hasegawa, Ibaraki, JP;

Yoshikazu Yonemitsu, Chiba, JP;

Yui Harada, Saitama, JP;

Assignees:

DNAVEC Corporation, Ibaraki, JP;

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/071 (2010.01); C12N 5/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides methods for producing DCs, which comprise the step of culturing DC precursor cells in the presence of multiple cytokines, dendritic cells produced thereby, and uses thereof. The methods of the present invention enable production of large quantities of DC precursors with a high ability to differentiate into DCs. The present invention enables one to obtain large quantities of DCs from a small number of DC precursor cells, and therefore makes it easier to increase the number of DCs for administration in DC-based anti-tumor immunotherapy, treatment of infection, and such. Thus, an enhancement is expected for the effect of DC vaccines.


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