The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 09, 2012
Filed:
Dec. 12, 2003
Joseph A. Sorge, Wilson, WY (US);
Reinhold Dietrich Mueller, San Diego, CA (US);
Gothami Padmabandu, San Diego, CA (US);
Nick Roelofs, San Diego, CA (US);
Holly H. Hogrefe, San Diego, CA (US);
Joseph A. Sorge, Wilson, WY (US);
Reinhold Dietrich Mueller, San Diego, CA (US);
Gothami Padmabandu, San Diego, CA (US);
Nick Roelofs, San Diego, CA (US);
Holly H. Hogrefe, San Diego, CA (US);
Agilent Technologies, Inc., Santa Clara, CA (US);
Abstract
The invention relates to the generation and characterization of Archaeal DNA polymerase mutants with deficient 3'-5′ exonuclease activity and reduced base analog detection activity. The invention further provides for Archaeal DNA polymerase mutants with deficient 3′-5′ exonuclease activity and reduced base analog detection activity containing additional mutations that modulate other DNA polymerase activities including DNA polymerization or reverse transcriptase activity. The invention also discloses methods and applications of DNA polymerases with deficient 3′-5′ exonuclease activity and reduced base analog detection activity.