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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8283131 B1

PDFFull Text
Expired
Date of Patent:
Oct. 09, 2012

Filed:

Oct. 28, 2008

Methods and kits for the rapid determination of patients at high risk of death during severe sepsis and septic shock

Applicants:

Didier Payen DE LA Garanderie, Paris, FR;

Anne-claire Lukaszewicz, Chantilly, FR;

Inventors:

Didier Payen De La Garanderie, Paris, FR;

Anne-Claire Lukaszewicz, Chantilly, FR;

Assignee:

Assistance Publique-Hopitaux de Paris, Paris, FR;

Attorney:

Alston & Bird LLP

Primary Examiner:

Gail R Gabel

Assistant Examiner:

James L Grun

Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/533 (2006.01); G01N 33/535 (2006.01); G01N 33/536 (2006.01); G01N 33/543 (2006.01); C07K 16/24 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides for the in vitro establishing of a prognosis for a subject in severe sepsis with at least two organ failures or in septic shock with at least two organ failures. Embodiments of the invention comprise the steps of measuring the level of the S100A8/A9 complex from a biological sample from a subject, and comparing the measured level to a predetermined threshold in which the measured level of the S100A8/A9 complex above the predetermined threshold is indicative of a bad prognosis and a measured level of the S100A8/A9 complex below the predetermined threshold is indicative of a good prognosis.

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Payen De La Garanderie, Didier. (2012). Methods and kits for the rapid determination of patients at high risk of death during severe sepsis and septic shock (U.S. Patent No. 8283131). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8283131

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