The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 09, 2012

Filed:

May. 31, 2006
Applicants:

Ralf Jochem, Bad Homburg, DE;

Franz Paul Armbruster, Bobenheim-Roxheim, DE;

Veit Braun, Mainz, DE;

Christoph Von Eichel-streiber, Schweppenhausen, DE;

Inventors:

Ralf Jochem, Bad Homburg, DE;

Franz Paul Armbruster, Bobenheim-Roxheim, DE;

Veit Braun, Mainz, DE;

Christoph Von Eichel-Streiber, Schweppenhausen, DE;

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/385 (2006.01); A01N 63/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention is relates to drugs on the basis of antibodies against non-cellular bone matrix proteins, especially BSP, for use in the prevention and treatment of bone metastases. According to the invention, the antibodies are induced in the patient by recombinantly expressing antigenic determinants of bone matrix proteins inand anchoring them on the surfaces thereof. The antigenic determinants are selected according to whether they are characteristic of antigens that are expressed by the tumor cells themselves.


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