The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 02, 2012
Filed:
Nov. 20, 2008
Applicants:
Ulrich Emde, Darmstadt, DE;
Oliver Block, Rossdorf, DE;
Kai Schiemann, Seeheim-Jugenheim, DE;
Inventors:
Assignee:
Merck Patent Gesellschaft mit beschränkter Haftung, Darmstadt, DE;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention relates to a novel process for preparing enantiomerically enriched or pure tetrahydroquinoline derivatives by reacting a chiral dihydropyran-methylamine C with a aldehyde B and an aniline A in a multicomponent one pot synthesis in the presence of a protonic acid or lewis acid with a suitable solvent. A, B, C have the meaning as described in the specification.