The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 02, 2012
Filed:
Dec. 20, 2007
Applicants:
Wang Bryan, Wyomissing, PA (US);
Frank Shi, Downingtown, PA (US);
Juliane Mills, Wallingford, PA (US);
Inventors:
Wang Bryan, Wyomissing, PA (US);
Frank Shi, Downingtown, PA (US);
Juliane Mills, Wallingford, PA (US);
Assignee:
Centocor, Inc., Malvern, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
Polypeptides comprising EGFR extracellular domains I-III capable of forming dimeric EGF-binding proteins are provided. The dimeric construct of the invention is useful in applications where high affinity EGF binding is desired and can be used to select agents capable of binding to native EGFR in the presence of EGF.