The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 02, 2012

Filed:

Sep. 17, 2009
Applicants:

Ling Jong, Sunnyvale, CA (US);

Faming Jiang, Mountain View, CA (US);

Gaoquan LI, Mountain View, CA (US);

Kristien Mortelmans, Los Altos Hills, CA (US);

Inventors:

Ling Jong, Sunnyvale, CA (US);

Faming Jiang, Mountain View, CA (US);

Gaoquan Li, Mountain View, CA (US);

Kristien Mortelmans, Los Altos Hills, CA (US);

Assignee:

SRI International, Menlo Park, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/40 (2006.01); A61K 31/33 (2006.01); A61K 31/00 (2006.01); A61K 31/445 (2006.01); A61K 31/41 (2006.01); C07D 491/00 (2006.01); C07D 257/04 (2006.01); C07D 249/08 (2006.01); C07D 205/00 (2006.01); C07D 211/32 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds useful as antibacterial agents are provided. The compounds are analogs of indole-3-carbinol and have a backbone selected from dihydroindolo[2,3-b]carbazole, 2,2'-diindolylmethane, 2′,3-diindolylmethane, and 3,3′-diindolylmethane. The compounds are useful therapeutic and prophylactic treatment of bacterial infections in mammals. Methods of synthesis of the compounds are provided, as are pharmaceutical compositions containing the compounds.


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