The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 02, 2012

Filed:

Jan. 14, 2009
Applicants:

Hisashi Narimatsu, Ibaraki, JP;

Masanori Gotoh, Ibaraki, JP;

Takashi Sato, Ibaraki, JP;

Inventors:

Hisashi Narimatsu, Ibaraki, JP;

Masanori Gotoh, Ibaraki, JP;

Takashi Sato, Ibaraki, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/54 (2006.01); C12N 15/63 (2006.01); C12Q 1/68 (2006.01); C12N 9/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

An enzyme which transfers N-acetylgalactosamine to N-acetylglucosamine via a β1-4 linkage was isolated and the structure of its gene was explained. This led to the production of said enzyme or the like by genetic engineering techniques, the production of oligosaccharides using said enzyme, and the diagnosis of diseases on the basis of said gene or the like. The present invention uses a protein having the amino acid sequence shown in SEQ ID NO: 1, 3, 26 or 27 in the Sequence Listing or a variant of said amino acid sequence wherein one or more acids are substituted or deleted, or one or more acids are inserted or added and having the activity of transferring N-acetylgalactosamine (GalNAc) to N-acetylglucosamine serving as a substrate via a β1-4 linkage and nucleic acids encoding said protein.


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