The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 02, 2012

Filed:

Oct. 09, 2008
Applicants:

Michael Detamore, Lawrence, KS (US);

Milind Singh, Mission, KS (US);

Aaron M. Scurto, Oskaloosa, KS (US);

Cory Berkland, Lawrence, KS (US);

Inventors:

Michael Detamore, Lawrence, KS (US);

Milind Singh, Mission, KS (US);

Aaron M. Scurto, Oskaloosa, KS (US);

Cory Berkland, Lawrence, KS (US);

Assignee:

The University of Kansas, Lawrence, KS (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61F 2/00 (2006.01); C12N 11/08 (2006.01); C12N 5/07 (2010.01);
U.S. Cl.
CPC ...
Abstract

A tissue engineering scaffold for growing cells can include a plurality of biocompatible microspheres linked together to form a three-dimensional matrix. The matrix can include a plurality of pores for growing cells. The biocompatible microspheres can include first and second sets of microspheres. The first set of microspheres can have a first characteristic, and a first predetermined spatial distribution with respect to the three-dimensional matrix. The second set of microspheres can have a second characteristic that is different from the first characteristic, and a second predetermined spatial distribution that is different from the first predetermined spatial distribution with respect to the three-dimensional matrix. The first and second characteristics can selected a composition, polymer, particle size, particle size distribution, type of bioactive agent, type of bioactive agent combination, bioactive agent concentration, amount of bioactive agent, rate of bioactive agent release, mechanical strength, flexibility, rigidity, color, radiotranslucency, radiopaqueness, or the like.


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