The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 02, 2012

Filed:

Apr. 20, 2007
Applicants:

Peter Bugelski, Pottstown, PA (US);

Anuk Das, Berwyn, PA (US);

Donald E. Griswold, North Wales, PA (US);

Bailin Liang, Gilbertsville, PA (US);

LI LI, Downingtown, PA (US);

Robert T. Sarisky, Lansdale, PA (US);

Xiaozhou Shang, West Chester, PA (US);

Inventors:

Peter Bugelski, Pottstown, PA (US);

Anuk Das, Berwyn, PA (US);

Donald E. Griswold, North Wales, PA (US);

Bailin Liang, Gilbertsville, PA (US);

Li Li, Downingtown, PA (US);

Robert T. Sarisky, Lansdale, PA (US);

Xiaozhou Shang, West Chester, PA (US);

Assignee:

Centocor, Inc., Malvern, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods of treating disorders related to CXCL13 activity utilize CXCL13 antagonists and, optionally, TNFα antagonists, such as antibodies, including specified portions or variants, polypeptides, polynucleotides, siRNA, shRNA, ribozymes, and DNAzymes. Disorders related to CXCL13 activity include inflammatory disorders, such as pulmonary disorders, for example, asthma, emphysema, and COPD, and systemic lupus erythematosus.


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