The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 25, 2012
Filed:
Jan. 08, 2010
Michael R. Knapp, Palo Alto, CA (US);
Jill M. Baker, Redwood City, CA (US);
Andrea W. Chow, Los Altos, CA (US);
Anne R. Kopf-sill, Portola Valley, CA (US);
Michael A. Spaid, Mountain View, CA (US);
Michael R. Knapp, Palo Alto, CA (US);
Jill M. Baker, Redwood City, CA (US);
Andrea W. Chow, Los Altos, CA (US);
Anne R. Kopf-Sill, Portola Valley, CA (US);
Michael A. Spaid, Mountain View, CA (US);
Caliper Life Sciences, Inc., Alameda, CA (US);
Abstract
Systems for differentiating the lengths of nucleic acids of interest in a sample are provided. The system includes a microfluidic device, a detector, and a software system. The microfluidic device includes an amplification microchannel or microchamber containing a reaction mixture under conditions that provide one or more amplicons of the nucleic acid of interest. The detector is integral with or proximal to the microfluidic device and is configured to detect the amplicons as one or more signals from a homogenous mixture. The software system interprets one or more coincidentally detected signals to indicate lengths of one or more individual nucleic acid molecules of interest, thereby differentiating the lengths of the nucleic acids of interest.