The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 25, 2012

Filed:

Mar. 08, 2010
Applicants:

Tatsumi Suzuki, Odawara, JP;

Tadashi Sugiura, Hiratsuka, JP;

Yoshikazu Ito, Naka-gun, JP;

Inventors:

Tatsumi Suzuki, Odawara, JP;

Tadashi Sugiura, Hiratsuka, JP;

Yoshikazu Ito, Naka-gun, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/41 (2006.01); C07D 257/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a process for preparation of 1-alkyl-5-benzoyl-1H-tetrazole derivative including a step 1 of reacting a ketoamide derivative represented by formula (I) (in formula (I), A represents a halogen atom or the like; n represents an integer of 0 to 5; Y represents an alkyl group) with a halogenating agent to obtain an imidoyl halide derivative represented by formula (II) (in formula (II), A, n and Y are as defined above; X represents a halogen atom); and a step 2 of reacting the imidoyl halide derivative represented by formula (II) with an azide represented by formula (III) (in formula (III), M represents an alkali metal or the like; m represents 1 or 2) to obtain a 1-alkyl-5-benzoyl-1H-tetrazole derivative represented by formula (IV) (in formula (IV), A, n and Y are as defined above).


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