The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 25, 2012
Filed:
Nov. 02, 2007
Applicants:
Shirley Ann Brunton, Berkshire, GB;
Oivin M. Guicherit, San Diego, CA (US);
Lawrence I. Kruse, Claremont, NH (US);
Inventors:
Shirley Ann Brunton, Berkshire, GB;
Oivin M. Guicherit, San Diego, CA (US);
Lawrence I. Kruse, Claremont, NH (US);
Assignee:
Curis, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/497 (2006.01); A61K 31/506 (2006.01); C07D 239/84 (2006.01); C07D 409/08 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention makes available methods and reagents for modulating proliferation or differentiation in a cell or tissue comprising contacting the cell with a compound. In certain embodiments, the methods and reagents may be employed to correct or inhibit an aberrant or unwanted growth state, e.g., by antagonizing a normal patched pathway or agonizing smoothened or hedgehog activity.