The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 25, 2012

Filed:

May. 13, 2009
Applicants:

Joffre B. Baker, Montara, CA (US);

Drew Watson, Los Altos, CA (US);

Tara Maddala, Redwood City, CA (US);

Steven Shak, Hillsborough, CA (US);

David J. Mauro, Redwood City, CA (US);

Shirin K. Ford, Redwood City, CA (US);

Inventors:

Joffre B. Baker, Montara, CA (US);

Drew Watson, Los Altos, CA (US);

Tara Maddala, Redwood City, CA (US);

Steven Shak, Hillsborough, CA (US);

David J. Mauro, Redwood City, CA (US);

Shirin K. Ford, Redwood City, CA (US);

Assignees:

Genomic Health, Inc., Redwood City, CA (US);

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides methods and compositions to facilitate determining whether an EGFR-expressing cancer in an individual is an EGFR inhibitor-responsive cancer, as well as methods for determining the likelihood that a patient having an EGFR-expressing cancer will exhibit a beneficial response to an EGFR inhibitor therapy. The methods generally involve determining a normalized expression level of a gene product that correlates with EGFR inhibitor responsiveness.


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