The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 25, 2012
Filed:
Oct. 05, 2007
Angeline Bartholomeusz, Carnegie, AU;
Margaret Littlejohn, Coburg, AU;
Anna Ayres, West Brunswick, AU;
Stephen Locarnini, East St Kilda, AU;
Angeline Bartholomeusz, Carnegie, AU;
Margaret Littlejohn, Coburg, AU;
Anna Ayres, West Brunswick, AU;
Stephen Locarnini, East St Kilda, AU;
Melbourne Health, Parkville, AU;
Abstract
The present invention relates generally to viral variants exhibiting reduced sensitivity to particular agents and/or reduced interactivity with immunological reagents. More particularly, the present invention is directed to hepatitis B virus variants exhibiting complete or partial resistance to nucleoside analogues and/or reduced interactivity with antibodies to viral surface components including reduced sensitivity. The present invention further contemplates assays for detecting such viral variants which assays are useful in monitoring anti-viral therapeutic regimes and in developing new or modified vaccines directed against viral agents and in particular hepatitis B virus variants.