The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 18, 2012

Filed:

Jun. 02, 2006
Applicants:

Scott Geromanos, Middletown, NJ (US);

Jeffrey Cruz Silva, Beverly, MA (US);

Hans Vissers, Huizen, NL;

Guo-zhong LI, Westborough, MA (US);

Inventors:

Scott Geromanos, Middletown, NJ (US);

Jeffrey Cruz Silva, Beverly, MA (US);

Hans Vissers, Huizen, NL;

Guo-Zhong Li, Westborough, MA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 30/04 (2006.01); G01N 30/00 (2006.01); G01N 30/26 (2006.01); G01N 30/72 (2006.01);
U.S. Cl.
CPC ...
Abstract

Absolute quantitation of protein in a sample is provided by comparing a sum or average of the N highest ionization intensities observed for peptides of a particular protein along with a calibration standard. The calibration standard can be in the form of a table generated by prior protein peptide analysis performed using one or more pre-determined proteins. The comparison is used to determine a corresponding absolute quantity of protein based on the observed sum or average of ionization intensities. A simple conversion factor can be applied to the calibration standard value to determine the absolute quantity of protein in the sample.


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