The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 18, 2012
Filed:
Jul. 03, 2010
Christophe Moinet, Noyal Chatillon, FR;
Liliane Halab, Laval, CA;
Nathalie Turcotte, Rosemere, CA;
Monica Bubenik, Mascouche, CA;
Marc Courchesne, Laval, CA;
Carl Poisson, Montreal, CA;
Oswy Z. Pereira, Kirkland, CA;
Paul Nguyen-ba, Laprairie, CA;
Bingcan Liu, Laval, CA;
Nathalie Chauret, Ile Bizard, CA;
Caroline Cadilhac, Montreal, CA;
Laval Chan Chun Kong, Kirkland, CA;
Christophe Moinet, Noyal Chatillon, FR;
Liliane Halab, Laval, CA;
Nathalie Turcotte, Rosemere, CA;
Monica Bubenik, Mascouche, CA;
Marc Courchesne, Laval, CA;
Carl Poisson, Montreal, CA;
Oswy Z. Pereira, Kirkland, CA;
Paul Nguyen-Ba, Laprairie, CA;
Bingcan Liu, Laval, CA;
Nathalie Chauret, Ile Bizard, CA;
Caroline Cadilhac, Montreal, CA;
Laval Chan Chun Kong, Kirkland, CA;
Vertex Pharmaceuticals Incorporated, Cambridge, MA (US);
Abstract
The invention relates to 21-keto triterpene compounds of formula (I): wherein R, X, and Y are as defined herein, and pharmaceutically acceptable salts and solvates thereof. These compounds exhibit significant anti-HIV activity. Thus, the invention also relates to methods for prevention or treatment of HIV infections by administering therapeutically effective amounts of a compound of formula (I), or a pharmaceutically acceptable salt or solvate thereof to a subject in need of such treatment.