The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8268974 B1

PDF
Full Text
Expired
Date of Patent:
Sep. 18, 2012

Filed:

Apr. 11, 2008
Applicants:

Shu-mei Liang, Maryland, MD (US);

Chun-yung Huang, Taipei, TW;

Yen-po Chen, Taipei, TW;

Chi-ming Liang, Taipei, TW;

Inventors:

Shu-Mei Liang, Maryland, MD (US);

Chun-Yung Huang, Taipei, TW;

Yen-Po Chen, Taipei, TW;

Chi-Ming Liang, Taipei, TW;

Assignee:

Academia Sinica, Taipei, TW;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 45/00 (2006.01); C07K 1/00 (2006.01); C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method for changing a globular protein structure into a fibrillar protein structure. The method comprising the steps of providing a globular protein, forming a solution containing the globular protein, adding a detergent to the solution containing the globular protein, applying the solution to a molecular sizing column with a pore size of at least 70 kDa and eluting with a solution containing detergent. A method for changing an unfolded protein structure into a fibrillar protein structure. The method comprising the steps of providing a globular protein, forming a solution containing the globular protein, adding a urea to the solution to unfold the globular protein, applying the solution to a molecular sizing column and eluting with a solution containing detergent. A method for treating cancer comprising the steps of providing a protein, changing the protein into a fibrillar structure, and administering a therapeutically effective amount of the fibrillar structure protein to a patient in need thereof. A method for producing a vaccine adjuvant or antigen adjuvant comprising the steps of providing a protein, and changing the protein into a fibrillar structure.


Find Patent Forward Citations

Loading…