The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 18, 2012

Filed:

May. 06, 2008
Applicants:

Tomasz Glinka, Cupertino, CA (US);

Olga Lomovskaya, Mountain View, CA (US);

Keith Bostian, Atherton, CA (US);

David M. Wallace, San Diego, CA (US);

Inventors:

Tomasz Glinka, Cupertino, CA (US);

Olga Lomovskaya, Mountain View, CA (US);

Keith Bostian, Atherton, CA (US);

David M. Wallace, San Diego, CA (US);

Assignee:

Rempex Pharmaceuticals, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 215/38 (2006.01); A61K 31/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed are compounds having at least one quaternary alkyl ammonium functionality. The compounds inhibit bacterial efflux pump inhibitors and are used in combination with an anti-bacterial agent to treat or prevent bacterial infections. These combinations can be effective against bacterial infections that have developed resistance to anti-bacterial agents through an efflux pump mechanism.


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