The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 18, 2012
Filed:
Sep. 20, 2011
Taro Terauchi, Tsukuba, JP;
Ayumi Takemura, Tsukuba, JP;
Takashi Doko, Tokyo, JP;
Yu Yoshida, Tsukuba, JP;
Toshiaki Tanaka, Tsukuba, JP;
Keiichi Sorimachi, Tsukuba, JP;
Yoshimitsu Naoe, Tsukuba, JP;
Carsten Beuckmann, Tsukuba, JP;
Yuji Kazuta, Tsukuba, JP;
Taro Terauchi, Tsukuba, JP;
Ayumi Takemura, Tsukuba, JP;
Takashi Doko, Tokyo, JP;
Yu Yoshida, Tsukuba, JP;
Toshiaki Tanaka, Tsukuba, JP;
Keiichi Sorimachi, Tsukuba, JP;
Yoshimitsu Naoe, Tsukuba, JP;
Carsten Beuckmann, Tsukuba, JP;
Yuji Kazuta, Tsukuba, JP;
Eisai R&D Management Co., Ltd., Tokyo, JP;
Abstract
A cyclopropane compound represented by the following formula (A) or a pharmaceutically acceptable salt thereof has orexin receptor antagonism, and therefore has a potencial of usefulness for the treatment of sleep disorder for which orexin receptor antagonism is effective, for example, insomnia: wherein Q represents —CH— or a nitrogen atom, Rand Reach independently represent a Calkyl group and the like, Rrepresents a hydrogen atom and the like, R, R, Rand Reach independently represent a hydrogen atom, a halogen atom, a Calkyl group and the like, R, Rand Reach independently represent a hydrogen atom, a halogen atom and the like, and Rrepresents a hydrogen atom and the like.