The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 18, 2012

Filed:

Feb. 11, 2009
Applicants:

Tsuyoshi Nagase, Tsukuba, JP;

Nagaaki Sato, Tsukuba, JP;

Akio Kanatani, Tsukuba, JP;

Shigeru Tokita, Tsukuba, JP;

Inventors:

Tsuyoshi Nagase, Tsukuba, JP;

Nagaaki Sato, Tsukuba, JP;

Akio Kanatani, Tsukuba, JP;

Shigeru Tokita, Tsukuba, JP;

Assignee:

MSD K.K., Chiyoda-Ku, JP;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61K 31/517 (2006.01); A01N 43/54 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a compound represented by formula (I) below, or a pharmaceutically acceptable salt thereof, which, having histamine H3 receptor antagonist or inverse agonist activity, is useful in the prophylaxis or therapy of metabolic diseases, circulatory diseases, or nervous system diseases. [where, for example, Ar is a divalent group formed by eliminating two hydrogen atoms from benzene, Xis a nitrogen atom, sulfur atom or oxygen atom, Ris a 5- to 6-membered heteroaryl group, Ring A is a 5- to 6-membered heteroaryl ring, Rand Rare amino groups or alkylamino groups, and Xis represented by formula (II): (where Rand Rare lower alkyl groups, and n is an integer from 2 to 4).]


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