The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 18, 2012
Filed:
Sep. 22, 2009
Birgitte L. Eriksen, Farum, DK;
Charlotte Hougaard, Bagsværd, DK;
Dan Peters, Malmö, SE;
Palle Christophersen, Ballerup, DK;
Birgitte L. Eriksen, Farum, DK;
Charlotte Hougaard, Bagsværd, DK;
Dan Peters, Malmö, SE;
Palle Christophersen, Ballerup, DK;
Neurosearch A/S, Ballerup, DK;
Abstract
Provided are substituted purinyl-pyrazol derivatives of the following formula (I), or a pharmaceutically acceptable salt thereof, and their use as potassium channel modulating agents, as well as pharmaceutical compositions having such derivatives that are useful for the treatment or alleviation of diseases or disorders associated with the activity of potassium channels: wherein Rrepresents hydrogen or alkyl; one of R, Rand Rrepresents alkyl, hydroxy-alkyl, alkoxy-alkyl, halo, trifluoromethyl, trifluoromethoxy, hydroxy or alkoxy; and the other two of R, Rand R, independently of each other, represent hydrogen, alkyl, hydroxy-alkyl, alkoxy-alkyl, halo, trifluoromethyl, trifluoromethoxy, hydroxy or alkoxy; Rrepresents phenyl optionally substituted with one or more substituents selected from the group consisting of alkyl, halo, trifluoromethyl, trifluoromethoxy, alkoxy and cyano; and Rrepresents R'OC(═O)—, wherein R′ represents alkyl, alkoxy, alkoxy-alkyl or adamantanyl.