The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 18, 2012
Filed:
May. 06, 2009
Applicants:
Jean-damien Charrier, Abingdon, GB;
Francesca Mazzei, Abingdon, GB;
David Kay, Abingdon, GB;
Andrew Miller, Abingdon, GB;
Inventors:
Jean-Damien Charrier, Abingdon, GB;
Francesca Mazzei, Abingdon, GB;
David Kay, Abingdon, GB;
Andrew Miller, Abingdon, GB;
Assignee:
Vertex Pharmaceuticals Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/14 (2006.01); A61K 31/4155 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention provides a facile process for the preparation of tri- and tetra-substituted pyrimidines. The process is useful for preparing inhibitors of protein kinases, especially Aurora kinase. These inhibitors are useful for treating or lessening the severity of Aurora-mediated diseases or conditions.