The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 18, 2012

Filed:

Apr. 18, 2012
Applicants:

Joerg Rosenberg, Ellerstadt, DE;

Ulrich Reinhold, Heidelberg, DE;

Bernd Liepold, Dossenheim, DE;

Gunther Berndl, Herxheim, DE;

Joerg Breitenbach, Mannheim, DE;

Laman Alani, Foster City, CA (US);

Soumojeet Ghosh, Gurnee, IL (US);

Inventors:

Joerg Rosenberg, Ellerstadt, DE;

Ulrich Reinhold, Heidelberg, DE;

Bernd Liepold, Dossenheim, DE;

Gunther Berndl, Herxheim, DE;

Joerg Breitenbach, Mannheim, DE;

Laman Alani, Foster City, CA (US);

Soumojeet Ghosh, Gurnee, IL (US);

Assignee:

Abbott Laboratories, Abbott Park, IL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 8/72 (2006.01); A61K 9/20 (2006.01); A61K 9/48 (2006.01); A61K 31/425 (2006.01); A61K 31/505 (2006.01);
U.S. Cl.
CPC ...
Abstract

A solid pharmaceutical dosage form providing improved oral bioavailability is disclosed for inhibitors of HIV protease. In particular, the dosage form comprises a solid dispersion of at least one HIV protease inhibitor and at least one pharmaceutically acceptable water-soluble polymer and at least one pharmaceutically acceptable surfactant, said pharmaceutically acceptable water-soluble polymer having a Tg of at least about 50° C. Preferably, the pharmaceutically acceptable surfactant has an HLB value of from about 4 to about 10.


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