The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 18, 2012
Filed:
Sep. 18, 2008
Jacqueline A. Kirchner, Seattle, WA (US);
Kenneth A. Brasel, Seattle, WA (US);
Kara Olson, White Plains, NY (US);
Jose Carlos Escobar, Sammamish, WA (US);
Dauphine Barone, Mill Creek, WA (US);
Jacqueline A. Kirchner, Seattle, WA (US);
Kenneth A. Brasel, Seattle, WA (US);
Kara Olson, White Plains, NY (US);
Jose Carlos Escobar, Sammamish, WA (US);
Dauphine Barone, Mill Creek, WA (US);
Amgen Inc., Thousand Oaks, CA (US);
Abstract
Antigen binding proteins that bind to human GM-CSF protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same are also provided. The antigen binding proteins can inhibit binding of GM-CSF to GM-CSFR, inhibit GM-CSF-induced proliferation and signaling of myeloid lineage cell lines and inhibit GM-CSF-induced activation of human monocytes.