The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 18, 2012
Filed:
Oct. 01, 2010
Martin Stelzle, Reutlingen, DE;
Brigitte Angres, Pfullingen, DE;
Massimo Kubon, Muensingen, DE;
Julia Schuette, Tuebingen, DE;
Britta Hagmeyer, Tuebingen, DE;
Felix Holzner, Langnau am Albis, CH;
Martin Stelzle, Reutlingen, DE;
Brigitte Angres, Pfullingen, DE;
Massimo Kubon, Muensingen, DE;
Julia Schuette, Tuebingen, DE;
Britta Hagmeyer, Tuebingen, DE;
Felix Holzner, Langnau am Albis, CH;
Abstract
A microfluidic system () for assembling and subsequently investigating complex cell arrangements has a three-dimensional microstructure () in which the cell culture is assembled, cultivated and investigated. At least two microchannel segments () through which the microstructure () can be perfused from outside with a medium () run in the microstructure (), whereby the microchannel segments () run at least in sections approximately parallel or equidistant to one another. The two microchannel segments () are separated from one another by a wall structure () in which at least one aperture () connecting the two microchannel segments () is provided. An electrode arrangement () is provided in or on the microstructure () in order to generate an inhomogeneous electric field () in the region of the at least one aperture (). A cell arrangement is assembled in this microstructure () by supplying medium () with cells () for assembling the cell culture in the microstructure (), with the inhomogeneous electric field () determined by the microstructure () bringing about the assembling of the cell arrangement from the supplied cells ().