The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 11, 2012
Filed:
Oct. 02, 2007
Kazuo Sekiguchi, Otsu, JP;
Takashi Suzuki, Otsu, JP;
Yutaka Ohbuchi, Otsu, JP;
Mitsuhiro Okuno, Otsu, JP;
Naoto Ohi, Otsu, JP;
Kenji Ohnishi, Otsu, JP;
Masaaki Motoyama, Otsu, JP;
Kenji Yoshida, Otsu, JP;
Takeshi Kodama, Otsu, JP;
Kazuhisa Sugiyama, Otsu, JP;
Seiji Akamatsu, Otsu, JP;
Kunihiko Kiyono, Otsu, JP;
Yasuo Yanagihara, Otsu, JP;
Takashi Watanabe, Otsu, JP;
Kazuhiko Hayashi, Otsu, JP;
Hideo Tanaka, Otsu, JP;
Takumi Sumida, Otsu, JP;
Kazuo Sekiguchi, Otsu, JP;
Takashi Suzuki, Otsu, JP;
Yutaka Ohbuchi, Otsu, JP;
Mitsuhiro Okuno, Otsu, JP;
Naoto Ohi, Otsu, JP;
Kenji Ohnishi, Otsu, JP;
Masaaki Motoyama, Otsu, JP;
Kenji Yoshida, Otsu, JP;
Takeshi Kodama, Otsu, JP;
Kazuhisa Sugiyama, Otsu, JP;
Seiji Akamatsu, Otsu, JP;
Kunihiko Kiyono, Otsu, JP;
Yasuo Yanagihara, Otsu, JP;
Takashi Watanabe, Otsu, JP;
Kazuhiko Hayashi, Otsu, JP;
Hideo Tanaka, Otsu, JP;
Takumi Sumida, Otsu, JP;
Otsuka Pharmaceutical Co., Ltd., Tokyo, JP;
Abstract
An object of the present invention is to provide a STAT3/5 activation inhibitor. The present invention provides a STAT3/5 activation inhibitor containing an aromatic compound represented by the general formula or a salt thereof as an active ingredient: wherein Xrepresents a nitrogen atom or a group —CH═, Rrepresents a group —Z—R, in which Z represents a group —CO—, a group —CH(OH)— or the like, Rrepresents a 5- to 15-membered monocyclic, dicyclic or tricyclic saturated or unsaturated heterocyclic group having 1 to 4 nitrogen atoms, oxygen atoms or sulfur atoms, Rrepresents a hydrogen atom or a halogen atom, Y represents a group —O—, a group —CO—, a group —CH(OH)— or a lower alkylene group, and A represents a group wherein Rrepresents a hydrogen atom, a lower alkoxy group or the like, p represents 1 or 2, Rrepresents an imidazolyl lower alkyl group or the like.