The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 11, 2012
Filed:
Aug. 15, 2007
Richard E. Pagano, Rochester, MN (US);
Robert Bittman, Roslyn Heights, NY (US);
David L. Marks, Rochester, MN (US);
Hirohito Kita, Rochester, MN (US);
Ramandeep S. Takhter, Rochester, MN (US);
Richard E. Pagano, Rochester, MN (US);
Robert Bittman, Roslyn Heights, NY (US);
David L. Marks, Rochester, MN (US);
Hirohito Kita, Rochester, MN (US);
Ramandeep S. Takhter, Rochester, MN (US);
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
Abstract
This disclosure provides a composition useful for inhibiting caveolar endocytosis, plasma membrane microdomain formation, virus binding and infection, transmembrane signaling, and integrin function in cells. The composition is composed of non-natural analogs of sphingolipids, and may have applications in the treatment or amelioration of diseases associated with caveolar endocytosis, plasma membrane microdomain formation, transmembrane signaling, and integrin function. Methods for making and using the described composition are also provided.