The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 11, 2012

Filed:

May. 26, 2005
Applicants:

Stephen F. Vatner, Barnegat Light, NJ (US);

Dorothy E. Vatner, Barnegat Light, NJ (US);

Junichi Sadoshima, Berkeley Heights, NJ (US);

Jayashree Pain, Livingston, NJ (US);

Inventors:

Stephen F. Vatner, Barnegat Light, NJ (US);

Dorothy E. Vatner, Barnegat Light, NJ (US);

Junichi Sadoshima, Berkeley Heights, NJ (US);

Jayashree Pain, Livingston, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/20 (2006.01); C07K 16/40 (2006.01); C07H 7/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to compositions and methods for diagnosing and treating cardiac conditions and neurodegenerative diseases using antibodies which specifically recognize and bind to the adenylyl cyclase 5 isoform in the heart and brain. These antibodies demonstrate high specificity to the AC5 isoform and do not cross react to any other AC5 isoform. The invention further relates to methods of delivery of drugs to the site of injured tissue using the antibodies of the present invention.


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