The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 11, 2012
Filed:
Feb. 05, 2007
David Martin Anderson, Gaithersburg, MD (US);
Andrew John Collis, Ulverston, GB;
Lin Liu, Gaithersburg, MD (US);
Sergey Podkovyrov, Gaithersburg, MD (US);
Christopher Preston, Ulverston, GB;
David Martin Anderson, Gaithersburg, MD (US);
Andrew John Collis, Ulverston, GB;
Lin Liu, Gaithersburg, MD (US);
Sergey Podkovyrov, Gaithersburg, MD (US);
Christopher Preston, Ulverston, GB;
Glaxo Group Limited, Greenford, Middlesex, GB;
Abstract
Novel organisms, including DNA construct host cell combinations, are disclosed. The organisms comprise a transcription unit (e.g. operon) comprising DNA sequences encoding for enzymes which promote the supply of single carbon units for the conversion of dUMP to dTMP. Examples include: dihydrofolate reductase genes e.g. T4 frd; Serine Hydroxymethyltransferase genes e.g. glyA; 3-phosphoglycerate dehydrogenase genes e.g. serA; and THF synthase genes e.g. ADE3. The organisms are used in a biological method of producing thymidine with significantly reduced levels of uridine.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile