The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 11, 2012

Filed:

Apr. 13, 2005
Applicants:

Masahiko Koike, Osaka, JP;

Hiroyoshi Koyama, Osaka, JP;

Naoru Hamaguchi, Osaka, JP;

Inventors:

Masahiko Koike, Osaka, JP;

Hiroyoshi Koyama, Osaka, JP;

Naoru Hamaguchi, Osaka, JP;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4439 (2006.01); A61K 31/155 (2006.01); A61K 9/201 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides a solid preparation containing an insulin sensitizer and an active ingredient (except insulin sensitizers), which shows in vivo dissolution behavior of an insulin sensitizer, which is similar to the dissolution behavior of an insulin sensitizer from 'a solid preparation containing an insulin sensitizer alone as an active ingredient'. The present invention provides a solid preparation containing (1) a layer containing an insulin sensitizer, and (2) a layer containing (a) an active ingredient (except insulin sensitizers), (b) microcrystalline cellulose having a mean particle size of 5-25 μm, (c) microcrystalline cellulose having a mean particle size of 30-100 μm and (d) polyvinylpyrrolidone K-90.


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