The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 11, 2012
Filed:
Jul. 11, 2005
Helmut Fiebig, Schwarzenbek, DE;
Martin Wald, Hamburg, DE;
Andreas Nandy, Hamburg, DE;
Helga Kahlert, Hamburg, DE;
Bernahrd Weber, Hamburg, DE;
Oliver Cromwell, Suesel-Fassendorf, DE;
Helmut Fiebig, Schwarzenbek, DE;
Martin Wald, Hamburg, DE;
Andreas Nandy, Hamburg, DE;
Helga Kahlert, Hamburg, DE;
Bernahrd Weber, Hamburg, DE;
Oliver Cromwell, Suesel-Fassendorf, DE;
Merck Patent GmbH, Darmstadt, DE;
Abstract
The present invention relates to the preparation and use of variants of the group 1 allergens of the Poaceae (sweet grasses) which are characterised by reduced IgE reactivity compared with the known wild-type allergens and at the same time by substantially maintained reactivity with T-lymphocytes. These hypoallergenic allergen variants can be employed for the specific immunotherapy (hyposensitisation) of patients having grass pollen allergy or for the preventive immunotherapy of grass pollen allergies.