The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 04, 2012

Filed:

Feb. 22, 2008
Applicants:

Susana Marto, Costa da Caparica, PT;

William Heggie, Pamela, PT;

Zita Mendes, Lisbon, PT;

Jose Rafael Antunes, Setubal, PT;

Inventors:

Susana Marto, Costa da Caparica, PT;

William Heggie, Pamela, PT;

Zita Mendes, Lisbon, PT;

Jose Rafael Antunes, Setubal, PT;

Assignee:

Hovlone Inter Limited, Lucerne, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 237/26 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides crystalline minocycline base. In particular, three crystalline polymorphic forms, designated Form I, Form II and Form III, of minocycline base are provided. These are characterized by XRD and IR data. Processes for preparing the new polymorphic forms are also provided. For example, Form I is prepared by dissolving and/or suspending amorphous minocycline base in an organic solvent chosen from ethers followed by crystallization from the mixture.


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