The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 04, 2012
Filed:
Mar. 22, 2012
Sanjiv S. Gambhir, Portollo Valley, CA (US);
Andreas M. Loening, Stanford, CA (US);
Anna M. Wu, Sherman Oaks, CA (US);
Sanjiv S. Gambhir, Portollo Valley, CA (US);
Andreas M. Loening, Stanford, CA (US);
Anna M. Wu, Sherman Oaks, CA (US);
The Board of Trustees of the Leland Stanford Junior University, Palo Alto, CA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
Briefly described, embodiments of this disclosure include polynucleotides that encode mutantluciferases that exhibit modulated properties as compared to the corresponding wild-type luciferases, and the modulated properties include at least one of: modulated stability; enhanced light output; and modulated emission maximum. Embodiments of the present disclosure also include polypeptides or fragments thereof encoded by the polynucleotides, constructs including the polynucleotide, expression cassettes, cells, methods of producing the polynucleotides and polypeptides, antibodies, transgenic cells and/or animals, kits, and the like.