The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 04, 2012
Filed:
Apr. 14, 2008
Charles Aylsworth, Holt, MI (US);
Siu-cheong Ho, East Lansing, MI (US);
David Juckett, East Lansing, MI (US);
John W. Judge, St. Johns, MI (US);
Barnett Rosenberg, Holt, MI (US);
Igor V. Zlatkin, Millis, MA (US);
Tatiana Zlatkin, Millis, MA (US);
Charles Aylsworth, Holt, MI (US);
Siu-Cheong Ho, East Lansing, MI (US);
David Juckett, East Lansing, MI (US);
John W. Judge, St. Johns, MI (US);
Barnett Rosenberg, Holt, MI (US);
Igor V. Zlatkin, Millis, MA (US);
Tatiana Zlatkin, Millis, MA (US);
Michigan State University, Lansing, MI (US);
Abstract
The present invention provides compositions and methods for the prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases, for stimulating an immune response in a subject, and for use as an alternative to interleukin-12 (IL-12) treatment. In particular, the present invention provides Apicomplexa-related proteins (ARPs) that have immune stimulatory activity and thus have uses in the treatment and prevention of cancer and infectious diseases and in immune modulation. Compositions comprising an ARP are provided. Methods of use of an ARP for the prevention and/or treatment of cancer and/or infectious diseases, for use as an alternative to interleukin-12 (IL-12) treatment, and for eliciting an immune response in a subject, are also provided.