The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 04, 2012
Filed:
Jun. 21, 2011
Applicants:
Andrew Ihor Korytko, Oceanside, CA (US);
David Matthew Marquis, Encinitas, CA (US);
Eric Michael Smith, San Diego, CA (US);
Barbara Anne Swanson, Encinitas, CA (US);
Inventors:
Andrew Ihor Korytko, Oceanside, CA (US);
David Matthew Marquis, Encinitas, CA (US);
Eric Michael Smith, San Diego, CA (US);
Barbara Anne Swanson, Encinitas, CA (US);
Assignee:
Eli Lilly and Company, Indianapolis, IN (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 16/00 (2006.01); C07K 16/18 (2006.01); C07K 16/22 (2006.01); C07K 16/24 (2006.01);
U.S. Cl.
CPC ...
Abstract
Humanized and chimeric antibodies are provided that specifically bind human sclerostin and are characterized as having high affinity and strong neutralizing properties. The antibodies of the invention are useful for increasing bone mass, bone mineral density and bone strength and for the treatment of various disorders, e.g., osteoporosis, in human subject.