The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 28, 2012
Filed:
Feb. 26, 2009
Applicants:
Hirofumi Maeda, Takasago, JP;
Akio Fujii, Takasago, JP;
Masaru Mitsuda, Takasago, JP;
Inventors:
Assignee:
Kaneka Corporation, Osaka, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 23/00 (2006.01); C07H 19/00 (2006.01); C07H 19/167 (2006.01); C07H 19/173 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to a method for producing a 2'-hydroxy-protected nucleoside derivative by reacting a ribonucleoside with an acylating or a carbamoylating reagent in the presence of a metal complex consisting of a copper compound and an optically active ligand. By the method according to the present invention, a 2′-hydroxy-protected ribonucleoside derivative, which is an important intermediate for producing an oligonucleoside, can be easily produced with good regioselectivity from a nucleoside derivative of which 2′,3′-hydroxy groups are not protected.