The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 28, 2012
Filed:
Nov. 18, 2011
Werngard Czechtizky, Frankfurt, DE;
Zhongli Gao, Flemington, NJ (US);
William Joseph Hurst, Oxford, NJ (US);
Lothar Schwink, Stadtallendorf, DE;
Siegfried Stengelin, Eppstein, DE;
Werngard Czechtizky, Frankfurt, DE;
Zhongli Gao, Flemington, NJ (US);
William Joseph Hurst, Oxford, NJ (US);
Lothar Schwink, Stadtallendorf, DE;
Siegfried Stengelin, Eppstein, DE;
SANOFI, Paris, FR;
Abstract
The present invention discloses and claims a series of substituted N-phenyl-bipyrrolidine carboxamides of formula (I). wherein R, R, R, Rand Rare as described herein. More specifically, the compounds of this invention are modulators of H3 receptors and are, therefore, useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of diseases modulated by H3 receptors including diseases associated with the central nervous system. Additionally, this invention also discloses methods of preparation of substituted N-phenyl-bipyrrolidine carboxamides and intermediates therefor.