The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 28, 2012
Filed:
Jul. 17, 2008
Haoyun an, Carlsbad, CA (US);
Biao Xi, San Diego, CA (US);
Yama Abassi, Temecula, CA (US);
Xiaobo Wang, San Diego, CA (US);
Xiao Xu, San Diego, CA (US);
Haoyun An, Carlsbad, CA (US);
Biao Xi, San Diego, CA (US);
Yama Abassi, Temecula, CA (US);
Xiaobo Wang, San Diego, CA (US);
Xiao Xu, San Diego, CA (US);
Acea Biosciences, Inc., San Diego, CA (US);
Abstract
Novel compounds having a fused bicyclic heteroaromatic ring system substituted with a heteroaryl five-membered ring are disclosed. The compounds inhibit growth of a variety of types of cancer cells, and are thus useful for treating cancer. Efficacy of these compounds is demonstrated with a system for monitoring cell growth/migration, which shows they are potent inhibitors of growth and/or migration of cancer cells. In addition, compounds of the invention were shown to stop growth of tumors in vivo, and to reduce the size of tumors in vivo. Compositions comprising these compounds, and methods to use these compounds and compositions for treatment of cancers, are disclosed.