The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 28, 2012
Filed:
Jan. 29, 2007
Drazen Raucher, Madison, MS (US);
Gene Bidwell, Iii, Jackson, MS (US);
Waldemar Priebe, Houston, TX (US);
Izabela Fokt, Houston, TX (US);
Drazen Raucher, Madison, MS (US);
Gene Bidwell, III, Jackson, MS (US);
Waldemar Priebe, Houston, TX (US);
Izabela Fokt, Houston, TX (US);
The University of Mississippi Medical Center, Jackson, MS (US);
Abstract
Elastin-like polypeptide (ELP) serves as a vector for thermally-targeted delivery of therapeutics, including cytotoxic chemotherapeutic drugs such as doxorubicin. Examples of an ELP-based delivery vehicle can comprise: (1) a cell penetrating peptide, such as a Tat peptide, (2) ELP, and (3) the lysosomally degradable glycylphenylalanylleucylglycine (GFLG) (SEQ ID NO: 3) spacer and a cysteine residue (SEQ ID NO: 4) conjugated to therapeutic such as doxorubicin, or an analog thereof.