The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 28, 2012

Filed:

Apr. 25, 2002
Applicants:

Shujiro Sakaki, Tsukuba, JP;

Kenshiro Shuto, Tsukuba, JP;

Mamoru Tsuchida, Noda, JP;

Yoshihiro Ashihara, Hannou, JP;

Mitsuo Isomura, Kawagoe, JP;

Inventors:

Shujiro Sakaki, Tsukuba, JP;

Kenshiro Shuto, Tsukuba, JP;

Mamoru Tsuchida, Noda, JP;

Yoshihiro Ashihara, Hannou, JP;

Mitsuo Isomura, Kawagoe, JP;

Assignee:

NOF Corporation, Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to an inhibitor capable of increasing accuracy of the reaction in hybridization, and inhibiting nonspecific hybridization, a clinical diagnostic reagent, and a method of clinical analysis whereby nonspecific hybridization in clinical analysis is inhibited, and a target nucleic substance is detected easily with high accuracy. The inhibitor and the clinical diagnostic reagent contains polymer (H) having a nonspecific hybridization inhibitory action. The polymer has in its molecule at least one of carboxyl and sulfone groups, and phosphorylcholine-like groups, and has a weight average molecular weight of 1000 to 5000000. The method of clinical analysis includes contacting a sample with a test agent capable of hybridizing with a specific nucleic substance in the presence of the inhibitor.


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